Preheat the oven to 375°F. In a 9 x 13-inch casserole dish spread a layer of Bolognese sauce and cover it with 2 Lasagne sheets. Top the Lasagne sheets with another layer of Bolognese sauce, evenly distributed, then top with Alfredo sauce and finely grated Parmigiano Reggiano cheese (around 1/5 of the quantity).
Repeat the steps to form 4 other layers. Top the last layer with Bolognese sauce, Alfredo sauce and a generous amount of grated Parmigiano Reggiano cheese. Bake until golden brown, around 20 minutes.